Detalhe da pesquisa
1.
Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation.
Cell
; 187(5): 1160-1176.e21, 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38382524
2.
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor.
Cell
; 184(8): 2121-2134.e13, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735609
3.
Ion transport in muscle acetylcholine receptor maintained by conserved salt bridges between the pore and lipid membrane.
Proc Natl Acad Sci U S A
; 121(16): e2320416121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588428
4.
Pathogenic residue insertion in neuronal nicotinic receptor alters intra- and inter-subunit interactions that tune channel gating.
J Biol Chem
; 300(5): 107266, 2024 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583864
5.
Nicotinic receptors in airway disease.
Am J Physiol Lung Cell Mol Physiol
; 326(2): L149-L163, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38084408
6.
Impact on AChR open channel noise by pore-peripheral salt bridge depends on voltage and divalent cations.
Biophys J
; 122(12): 2430-2444, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37113056
7.
Functional α7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics.
Am J Physiol Lung Cell Mol Physiol
; 325(1): L17-L29, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37192375
8.
NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4ß2 acetylcholine receptor.
Cell Mol Life Sci
; 78(4): 1565-1575, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32676916
9.
Genetic Variant in Nicotinic Receptor α4-Subunit Causes Sleep-Related Hyperkinetic Epilepsy via Increased Channel Opening.
Int J Mol Sci
; 23(20)2022 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36292983
10.
Potentiation of a neuronal nicotinic receptor via pseudo-agonist site.
Cell Mol Life Sci
; 76(6): 1151-1167, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30600358
11.
End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.
Physiol Rev
; 92(3): 1189-234, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22811427
12.
α4ß2 Nicotinic Acetylcholine Receptors: RELATIONSHIPS BETWEEN SUBUNIT STOICHIOMETRY AND FUNCTION AT THE SINGLE CHANNEL LEVEL.
J Biol Chem
; 292(7): 2729-2740, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28031459
13.
Investigation of Congenital Myasthenia Reveals Functional Asymmetry of Invariant Acetylcholine Receptor (AChR) Cys-loop Aspartates.
J Biol Chem
; 291(7): 3291-301, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26698174
14.
Stoichiometry for activation of neuronal α7 nicotinic receptors.
Proc Natl Acad Sci U S A
; 110(51): 20819-24, 2013 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24297903
15.
Stoichiometry for drug potentiation of a pentameric ion channel.
Proc Natl Acad Sci U S A
; 110(16): 6595-600, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23576748
16.
Detection and trapping of intermediate states priming nicotinic receptor channel opening.
Nature
; 459(7245): 451-4, 2009 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19339970
17.
Inter-residue coupling contributes to high-affinity subtype-selective binding of α-bungarotoxin to nicotinic receptors.
Biochem J
; 454(2): 311-21, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23802200
18.
Complex between α-bungarotoxin and an α7 nicotinic receptor ligand-binding domain chimaera.
Biochem J
; 454(2): 303-310, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23800261
19.
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br J Pharmacol
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454578
20.
Nicotinic receptor transduction zone: invariant arginine couples to multiple electron-rich residues.
Biophys J
; 104(2): 355-67, 2013 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23442857